Active vs Inactive Ingredients in Skincare

The Difference Between Active vs. Inactive Functional Ingredients in Skincare Formulations

Skincare isn't just about what individual ingredients do; it's ultimately about how they work together in the final formulation.

Following on from a previous blog about "How To Read and Understand Skincare Ingredient Lists / INCIs" we are going to do a deeper dive into the different types of ingredients that you find on your INCI.

In today's blog we're exploring the difference between 'active' ingredients and "inactive" (functional) ingredients on your skincare ingredient list (INCI) so that you can know more about the science behind your favourite products and how they fit and work together in a formulation.

We debunk some skincare and ingredient myths, explain the fascinating science of Rheology, explore why the idea of "fillers" in skincare is a myth, and list out some examples of active and "inactive" ingredients used in skincare and cosmetics.

*** There is also a sample Retinal & Peptide serum formulation at the end if you want to see what this looks like.


Skincare Formulation Is a Fascinating Blend of Disciplines

When I look at what cosmetic scientists and formulators do what comes to mind is a carefully orchestrated dance of science, art, and something just a little bit magical.

I like to think of it as 97% science - the precision of chemistry and biology; 2% art - the creativity in texture and feel - and 1% magic - that inexplicable spark that transforms ingredients into something truly special.

Ok - I know it's actually all science, but I've seen chemists work magic with a formulation with tricks of the trade up their sleeve and years of experience. If you ever get the chance to be in the lab where these formulations are created I'd recommend it.

In our previous blog we talked about "How to read the Ingredient list (INCI) on your product packaging".

Today, we're diving deeper into the actual ingredients that are listed and a crucial distinction: the difference between "active" and "inactive" (functional) ingredients.

Personally I disagree with this description because the ingredients typically described as "inactive" are anything but - every ingredient in your formulation has a role and purpose so there really is no such thing as an "inactive" ingredient.

Saying that - I do understand the sentiment or reason for describing it this way because we do need to make the distinction and it's an important part of reading your ingredient list.

We know that it is the well-known, much talked about "active" ingredients like the Retinoids and Vitamin C's and peptides that get all the limelight, but today we're also talking about the rest of the ingredients in your product that don't get recognised as much.


The Science of Rheology in Skincare

"Active" ingredients aside for a moment - there is a huge field in science called Rheology - the science of how materials flow and deform. In cosmetic science, rheology is absolutely crucial.

It dictates how a product feels on your skin, how easily it spreads, and how effectively it delivers its active ingredients.

In essence, Rheology is the bridge between a product's formulation and its performance.

Cosmetic chemists carefully manipulate rheological properties to create products that not only deliver effective results but also provide a pleasant and luxurious user experience.

They use a variety of functional ingredients, like viscosity enhancers, emulsifiers, and stabilisers, to achieve the desired rheological profile.

We cover this category further down in the blog so you can see how these ingredients work alongside your "active" ingredients to create a fully formed product that is stable, pleasant to use and supports the results that you're getting.

Understanding this difference will empower you to make informed choices about your skincare, ensuring you're getting the results you desire.


Before We Dive In: Debunking Some Important Skincare Myths

Before we dive into the main part of the blog I feel it's important to debunk a few important points about ingredients used in skincare.

1. Addressing the "Chemical-Free" Skincare Myth: A Scientific Reality Check

One of the most misleading and frankly, scientifically inaccurate, marketing claims in the skincare industry is the notion of being "chemical-free." If a brand uses this it should be a big red flag as it shows a misunderstanding of basic chemistry and I would have questions about this.

This phrase preys on consumer fears, implying that "chemicals" are inherently harmful.

The reality is that everything is a chemical. Water (H₂O), the air we breathe (a mixture of gases), and the natural oils derived from plants are all composed of chemicals.

To suggest that a product is "chemical-free" is not only misleading but fundamentally impossible.

In fact, if a product truly contained no chemicals, it wouldn't exist.

Brands using this term are exploiting a lack of scientific understanding and fostering unnecessary fear.

It's time to embrace the reality that chemistry is the foundation of everything, including the very products designed to enhance our skin's health, longevity and beauty.

2. Natural vs. Synthetic: Understanding the Difference - and the Myth That "Natural Is Better / Safer"

Another common misconception is that "natural" ingredients are safer and superior to "synthetic" ones.

I've found over the years that when someone asks me about "chemicals" in a product, it often refers to a "synthetic" ingredient - not always, but it has happened often enough.

While natural ingredients can offer valuable benefits, it's crucial to understand that "natural" does not automatically equate to "safe" or "effective."

A very well-known example is Poison Ivy - which is natural, but you wouldn't put it on your face.

Similarly, synthetic ingredients are created in a lab - they undergo rigorous testing and can be purer and more consistent than their natural counterparts. They are also often much more environmentally friendly and sustainable as they don't make use of natural resources.

Natural Ingredients:

  • Derived from plants, minerals, or animal sources.
  • Can be complex mixtures of various compounds.
  • May vary in quality and potency depending on sourcing and processing.
  • Can be potential allergens due to their complexity.

Synthetic Ingredients:

  • Created in a laboratory through chemical synthesis.
  • Can be precisely controlled for purity and consistency.
  • Often undergo extensive safety testing.
  • Can be designed to mimic or improve upon natural ingredients.
  • Can be more sustainable than natural counterparts.

The choice between natural and synthetic ingredients should be based on scientific evidence, safety data, and efficacy, not on fear-mongering marketing claims.

I've also seen brands who claim that they are all "natural" just to spot a peptide or some other synthetically derived ingredient(s) on an ingredient list.

Many synthetic ingredients are nature-identical and are created to be a pure and safe version of a natural ingredient.

Every brand has its own philosophy when it comes to its ingredient choices and how it communicates that to its customers.

I can only speak for myself - and at Beauty by Ané Skincare our approach is to use a combination of natural and synthetically derived ingredients because I believe that gives us the best opportunity to create the high-performance skincare that we want to offer you.

I love the benefits that ingredients like Retinaldehyde, different types of peptides, Vitamin C derivatives and several other synthetic options can safely bring to our formulations - and most importantly to our customers and their skin concerns and goals. (If you're interested in how these powerhouse ingredients work, keep an eye out for our upcoming three-part Retinoids series, and check out our Vitamin C series for a deep dive into C derivatives.)

I also love that we are in a position where modern science allows us to combine some of the best, cutting-edge synthetic ingredients with natural ingredients like botanical oils and extracts that have been around for centuries - and that we can bring all of this together in one formulation to offer you the best products we can and support you in your skin journey.

To me, this is an ideal path to follow, but it's important that we all have the relevant information to make the best decisions according to our own needs.

It's a decision only you can make. Always reach out to the brand directly if you have any questions about this.

3. Addressing the Misconception: "Active" vs. "Inactive" and the Myth of "Fillers"

As we've seen above it's common to hear skincare ingredients categorised as "active" and "inactive," implying that the latter are simply fillers or unnecessary components.

This is a significant misconception. In reality, functional ingredients are far from 'inactive'; they are essential for the product's efficacy, stability, and user experience.

The Problem with "Inactive":

  • The term "inactive" suggests that these ingredients have no role in the product's performance and/or can have no impact on the skin.
  • This misrepresentation undervalues the critical functions they perform.
  • It can lead consumers to believe that only "active" ingredients matter, which is far from the truth.

Functional Ingredients: The Unsung Heroes:

  • Functional ingredients are the backbone of any skincare formulation.
  • They ensure that the active ingredients are delivered effectively and safely.
  • They contribute to the product's texture, spreadability, and absorption.
  • They play a vital role in preserving the product's stability and shelf life.

4. Debunking the Myth of "Fillers" in Skincare

The notion that some ingredients are merely "fillers" is a myth that I want to address head-on, because it comes up a lot - and it does a real disservice to the science behind your products.

Every ingredient in a well-formulated product serves a purpose:

  • Solvents are not just "fillers"; they are essential for dissolving and dispersing other ingredients.
  • Viscosity enhancers are not just there to make a product thick - they help control the release of the active ingredients and create a pleasing skin feel.
  • Emulsifiers allow oil and water to mix, creating stable creams and lotions.
  • Preservatives are crucial for preventing bacterial and fungal growth, ensuring product safety.
  • Each ingredient is carefully selected to contribute to the overall effectiveness and usability of the product.

Every Ingredient Has a Purpose - and a Cost

Here's something that I think would change the "filler" conversation entirely if more people understood it: every single ingredient in a formulation costs money to be there.

Raw materials are purchased, tested, and carefully dosed. No formulator - and no brand - is putting an ingredient into a product just to "fill space." That would be a waste of money, it would compromise the formulation, and frankly, it would make no sense from a business perspective either.

In fact, formulations are so tightly balanced that sometimes even a 0.1% change in a single ingredient can alter the texture, the stability, the pH, or how well the active ingredients are delivered.

I've seen formulations where adjusting a viscosity enhancer by a fraction of a percent changed how the product felt on the skin entirely - or where a tiny shift in emulsifier concentration caused a previously stable emulsion to separate.

This is precision work. When a formulator includes an ingredient at, say, 0.3%, that number isn't arbitrary.

It's been tested, adjusted, and validated - often through multiple rounds of lab trials - to ensure it does exactly what it needs to do in that specific formulation, at that specific level, alongside every other ingredient present.

So when you see a long ingredient list, what you're actually looking at is the result of careful, deliberate formulation science - not padding.

Every line on that INCI represents a decision, a cost, and a function. 


What Are "Active" Ingredients In Skincare?

Active ingredients are the workhorses of your skincare routine.

There are thousands of different ingredients and their derivatives on the market so we will cover only the main categories/ingredient families with some of the more well-known and familiar examples.

These are the components proven to address specific skin concerns.

 They're the ingredients that deliver the promised results, whether it's reducing wrinkles and fine lines, clearing acne, or brightening hyperpigmentation.

Purpose:

  • Target specific skin concerns.
  • Can produce measurable changes in the skin.
  • Backed by scientific research and clinical trials.

A Quick Note on Concentration and 'Fairy dusting' 

One thing worth understanding is that "active" doesn't just mean "present" - the concentration matters enormously.

An ingredient can appear on an INCI list but be present at a level too low to deliver its researched benefits (sometimes called a "dusting" in formulation). While exact percentages aren't always disclosed on packaging, here are some general research-backed ranges to be aware of:

  • Vitamin C (L-Ascorbic Acid): Most studies show efficacy between 10-20%, with benefits plateauing around 20%.
  • Niacinamide: Effective from around 2-5%, with many products using up to 10%.
  • Retinol: Typically 0.3-1% for over-the-counter products; higher concentrations are available but require careful introduction.
  • Retinaldehyde: Effective at much lower concentrations - typically 0.05-0.1% - because it converts to retinoic acid in just one step (compared to retinol's two-step conversion process).
  • Glycolic Acid: Around 5-7% for daily use products; 20-30% for professional-grade treatments.
  • Salicylic Acid: Typically 0.5-2% in over-the-counter products.
  • Hyaluronic Acid: Usually formulated at 0.1-2%; higher isn't necessarily better.

These ranges are general guides based on published research - actual effective concentrations can vary depending on the full formulation, the delivery system, the pH, and how the ingredient interacts with everything else in the product.

This is why formulation matters so much, and why the same ingredient at the same percentage can perform very differently in two different products.

Examples of Active Ingredients:

1. Retinoids (Vitamin A Derivatives):

Retinol, Tretinoin, Retinaldehyde, Retinyl Palmitate

Stimulate collagen production, reduce wrinkles, improve texture, treat acne.

We have a comprehensive three-part Retinoids series coming soon that will go much deeper into this incredible ingredient family - stay tuned.

2. Alpha Hydroxy Acids (AHAs):

Glycolic Acid, Lactic Acid, Malic Acid, Tartaric Acid, Citric Acid

Exfoliate, improve texture, reduce hyperpigmentation.

3. Beta Hydroxy Acids (BHAs):

Salicylic Acid

Exfoliate pores, treat acne, reduce oil production.

4. Antioxidants:

Purpose: Neutralise free radicals, protect against environmental damage, reduce signs of ageing, soothe inflammation.

Vitamin-Based Antioxidants:

  • Vitamin C (L-Ascorbic Acid, Ascorbyl Glucoside, Sodium Ascorbyl Phosphate) - check out our three-part Vitamin C series for a full deep dive into these derivatives and how they differ.
  • Vitamin E (Tocopherol, Tocopheryl Acetate)
  • Niacinamide (Vitamin B3)

Plant Extract Antioxidants:

  • Green Tea Extract (Camellia Sinensis)
  • Resveratrol (from grapes)
  • Grape Seed Extract
  • Licorice Root Extract
  • Pomegranate Extract

5. Brighteners/Anti-Pigmentation: Reduce hyperpigmentation, even skin tone, and brighten complexion.

  • Kojic Acid
  • Azelaic Acid
  • Arbutin
  • Niacinamide
  • Licorice Root Extract
  • Tranexamic Acid - an increasingly popular option because it works by inhibiting melanin transfer rather than through exfoliation, making it suitable for sensitive skin and safe to use alongside other actives.
  • Hydroquinone (prescription only)

6. Humectants: Attract and retain moisture in the skin.

  • Hyaluronic Acid (Sodium Hyaluronate) - capable of holding up to 1,000 times its weight in water.
  • Glycerin
  • Aloe Vera
  • Propylene Glycol

7. Emollients (Including Plant Oils, EFAs, and Sterols): Soften, smooth, and moisturise the skin; strengthen the skin barrier. (For a deeper dive into how these ingredients support your barrier, see our dedicated Ceramides blog and our Barrier Health blog.)

Plant Oils:

  • Jojoba Oil
  • Argan Oil
  • Rosehip Oil
  • Squalane (derived from olives)

Essential Fatty Acids (EFAs):

  • Linoleic Acid (Omega-6)
  • Alpha-Linolenic Acid (Omega-3)

Sterols:

  • Cholesterol
  • Phytosterols

8. Occlusives: Form a protective barrier on the skin's surface, preventing moisture loss.

  • Petrolatum
  • Mineral Oil
  • Beeswax
  • Silicones (Dimethicone, Cyclopentasiloxane)

9. Peptides (Various Types): Improve skin firmness, reduce wrinkles, and enhance skin repair.

  • Signal Peptides: Stimulate collagen and elastin production (e.g., Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7)
  • Carrier Peptides: Deliver copper and other trace elements to the skin (e.g., Copper Tripeptide-1)
  • Neurotransmitter-Inhibiting Peptides: Reduce muscle contractions, minimising wrinkles (e.g., Acetyl Hexapeptide-8)
  • Enzyme-Inhibiting Peptides: Inhibit enzymes that break down collagen (e.g., Soy Peptide)
  • Barrier-Strengthening Peptides: Enhance the skin's natural defensive barrier.

10. Growth Factors:

Proteins that stimulate cellular growth and repair. Examples: Epidermal Growth Factor (EGF), Transforming Growth Factor (TGF).

Purpose: Promote collagen production, improve skin elasticity, accelerate wound healing.

11. Exosomes:

Extracellular vesicles released by cells that carry various molecules, including proteins and nucleic acids.

Purpose: Facilitate cell-to-cell communication, promote skin regeneration, and reduce inflammation.

Emerging Actives to Watch

The skincare ingredient landscape is constantly evolving, and there are some exciting newcomers gaining serious traction in research and in formulations. A few worth knowing about:

  • PDRN (Polydeoxyribonucleotide): Originally used in wound healing and regenerative medicine, PDRN supports tissue repair and cellular regeneration. It's become a major ingredient in Korean skincare and is rapidly gaining global attention.
  • Ectoin: A natural amino acid produced by microorganisms that thrive in extreme environments. It's a powerful moisture-locking and barrier-strengthening ingredient with strong anti-inflammatory properties.
  • Beta-Glucan: A polysaccharide with impressive hydrating and skin-soothing properties. Research shows it can support the skin's natural repair processes and calm inflammation - and it's well-tolerated by sensitive skin types.
  • Postbiotics: While probiotics and prebiotics have had their moment, postbiotics (the beneficial byproducts of bacterial fermentation) are emerging as a more stable, shelf-friendly option for supporting the skin's microbiome, calming irritation, and strengthening barrier function.

This is an area of skincare science that's moving quickly, and we'll be exploring some of these ingredients in more detail in future blogs.


What Are "Inactive" (Functional) Ingredients In Skincare?

Also known as "Inactive" Ingredients - I'm sure you'll see below that they do work very hard in your formulation and that's why I prefer to refer to them as 'Functional' ingredients.

Functional ingredients are the supporting cast of your skincare products. They don't directly address skin concerns, but they're essential for the product's texture, stability, and overall usability.

Purpose:

  • Enhance the product's texture and feel.
  • Ensure the product's stability and shelf life.
  • Facilitate the delivery of active ingredients.

Functionality:

  • Influence the product's viscosity, emulsification, and preservation.
  • Create a pleasant user experience.

Examples of Functional Ingredients:

Solvents (Water, Glycerin, Propylene Glycol):

  • Dissolve other ingredients.
  • Form the base of many skincare products.

Emulsifiers (Cetearyl Alcohol, Polysorbate 20, Stearic Acid):

  • Blend oil and water-based ingredients.
  • Create stable emulsions (creams, lotions).

Preservatives (Phenoxyethanol, Parabens, Potassium Sorbate):

  • Prevent bacterial and fungal growth.
  • Extend the product's shelf life.

Viscosity Enhancers (Carbomer, Xanthan Gum, Cellulose Gum):

  • Thicken the product's texture.
  • Improve spreadability and application.

Stabilisers (Citric Acid):

  • Maintain the product's pH and prevent ingredient degradation.
  • Prevent unwanted chemical reactions.

Humectants (Glycerin, Hyaluronic Acid, Propylene Glycol):

  • Draw moisture to the skin.
  • Increase skin hydration.
  • Note: some humectants are also active ingredients - these are a great example of why the "active" vs. "inactive" distinction doesn't always hold up neatly.

Emollients (Shea Butter, Jojoba Oil, Squalane):

  • Soften and smooth the skin.
  • Create a protective barrier.

Occlusives (Petrolatum, Mineral Oil, Beeswax):

  • Form a barrier on the skin's surface.
  • Prevent moisture loss.

pH Adjusters (Citric Acid, Sodium Hydroxide):

  • Balance the acidity or alkalinity of the product.
  • Ensure optimal product performance. This is particularly important for pH-dependent actives like Vitamin C (which typically needs a pH below 3.5 to penetrate effectively) and AHAs (which work best at a pH of 3-4).

Chelating Agents (Sodium Phytate, Tetrasodium Glutamate Diacetate):

  • Bind to metal ions (like iron and copper) that can be present in water or raw materials, preventing them from reacting with other ingredients in the formulation.
  • This matters because trace metals can degrade active ingredients - particularly antioxidants like Vitamin C and Vitamin E - causing them to lose efficacy and the product to discolour or destabilise. Chelating agents quietly protect the integrity of the entire formulation.

A Note on Ingredient Compatibility

Something that doesn't get talked about enough is that not all active ingredients play well together - and this is another area where functional ingredients and smart formulation come into play.

A few general guidelines worth knowing:

  • Retinoids + AHAs/BHAs: Using these together can increase irritation, especially when you're starting out. Many dermatologists recommend using them at different times (e.g., acids in the morning, retinoid at night) or on alternating nights.
  • Vitamin C + Niacinamide: Despite an old myth that these can't be combined, modern research and formulation science have shown they work well together. Many products now combine them successfully.
  • Vitamin C + Vitamin E + Ferulic Acid: These work synergistically - Vitamins C and E stabilise each other, and ferulic acid boosts their photoprotective effects. This is a well-researched combination.
  • Hyaluronic Acid: Plays well with virtually everything - it's one of the most compatible and versatile ingredients in skincare.

How ingredients are formulated together - the pH, the delivery system, the order of addition, the emulsion type - can make the difference between a product where actives compete with each other and one where they complement each other beautifully. This is a big part of what separates a well-made product from one that just has impressive-sounding ingredients on the label.


Multifunctional Ingredients: Bridging the Gap

Now, this is where it gets extra interesting - because we also have lots of ingredients that are 'multifunctional'. That means that while they can be used as a 'functional' ingredient, i.e., an emulsifier - they have also been proven to have a significant effect on certain skin concerns and they can benefit the skin the way an 'active' ingredient can.

This category highlights ingredients that serve essential functional roles in a formulation while also providing clinically proven skin benefits. These ingredients contribute to the product's texture, stability, and overall usability while simultaneously delivering targeted results.

Examples of Multifunctional Ingredients:

Olivem 1000 (Cetearyl Olivate, Sorbitan Olivate):

  • Functional: Emulsifier, creates lamellar liquid crystals that mimic the skin's lipid structure.
  • Active: Provides deep hydration, improves skin elasticity, and offers a silky, non-greasy feel.

Hyaluronic Acid:

  • Functional: Humectant, viscosity enhancer.
  • Active: Hydrates, plumps, and reduces the appearance of fine lines.

Niacinamide (Vitamin B3):

  • Functional: Stabiliser, viscosity enhancer.
  • Active: Reduces redness, strengthens the skin barrier (research has shown it can boost ceramide synthesis by several fold), minimises pores, brightens skin.

Glycerin:

  • Functional: Humectant, solvent.
  • Active: Hydrates, improves skin barrier function.

Squalane (Derived from olives or sugarcane):

  • Functional: Emollient, occlusive (light).
  • Active: Hydrates, soothes, and protects the skin; antioxidant properties.

Ceramides:

  • Functional: Emollient, skin-identical ingredient.
  • Active: Restores the skin barrier, reduces dryness and irritation. Ceramides are a major component of the skin's lipid matrix - they make up roughly 50% of the stratum corneum's lipid composition, which is why replenishing them topically can have such a significant impact. (We go much deeper into the science of ceramides in our dedicated Ceramides blog if you want to learn more.)

Panthenol (Pro-Vitamin B5):

  • Functional: Humectant, emollient.
  • Active: Soothes, hydrates, and promotes skin healing.

Certain Plant Oils (e.g., Jojoba, Argan):

  • Functional: Emollients, occlusives (light).
  • Active: Provide essential fatty acids, antioxidants, and anti-inflammatory benefits.

Sample Formulation: Retinaldehyde & Peptide Brightening Serum

Below is a SAMPLE formulation and a hypothetical manufacturing method to show you the combination of Active and Functional ingredients in a formulation.

  • You will note that there is a Water Phase and an Oil Phase in the formulation - that is because some ingredients are water-based/water-soluble and others are oil-based/oil-soluble.
  • When you combine water-based and oil-based ingredients in a formulation, it forms what we call an emulsion and based on the viscosity this can be a thin serum or a thicker cream and anything in between.
  • This is where 'functional' ingredients like emulsifiers play an important role as they facilitate the blending between water and oil-based ingredients so that the formulation doesn't separate. They can also impact the viscosity of the formulation and can work alongside viscosity enhancers to alter the texture of the formulation.
  • Whenever there is water and water-based ingredients in a formulation we need preservatives to keep the product free from pathogens and mould for example. An oil-based formulation like a face oil or cleansing balm/oil does not require a preservative system.

Note on the percentages below: You'll see that every ingredient has a specific percentage. These aren't arbitrary - they represent careful formulation decisions. As we discussed earlier, even a 0.1% shift in one ingredient can change the texture, stability, or performance of the entire product. The percentages in a formulation always add up to 100%, and adjusting one means adjusting others to compensate. This is the precision work that goes into every product you use.

SAMPLE Retinaldehyde & Peptide Brightening Serum - Emulsion Formulation:

Phase A (Water Phase):

  • Water (Aqua): 72.35% - Functional: Solvent, base of the formulation. Water is typically the "q.s." (quantum satis - meaning "quantity sufficient") ingredient, adjusted to bring the total formulation to exactly 100%.
  • Glycerin: 5.0% - Multifunctional: Humectant (draws moisture), solvent, viscosity enhancer.
  • Niacinamide: 3.0% - Multifunctional: Brightener, strengthens skin barrier, reduces redness.
  • Sodium Hyaluronate (Hyaluronic Acid): 0.5% - Multifunctional: Humectant, hydrates, plumps.
  • Xanthan Gum: 0.3% - Functional: Viscosity enhancer, thickener, stabiliser.

Phase B (Oil Phase):

  • Squalane: 5.0% - Multifunctional: Emollient, light occlusive, hydrates, antioxidant.
  • Jojoba Oil: 3.0% - Multifunctional: Emollient, provides essential fatty acids.
  • Cetearyl Olivate, Sorbitan Olivate (Olivem 1000): 4.0% - Multifunctional: Emulsifier, provides hydration and a silky feel.
  • Cetyl Alcohol: 1.0% - Functional: Co-emulsifier, viscosity enhancer.

Phase C (Active Phase):

  • Retinaldehyde: 0.05% - Active: Stimulates collagen production, reduces wrinkles, and improves texture. (At 0.05%, this is within the effective range for retinaldehyde - remember, it converts to retinoic acid in one step, making it significantly more potent than retinol at comparable concentrations.)
  • Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7: 3.0% - Active: Signal peptides, stimulate collagen and elastin production.
  • Licorice Root Extract: 1.0% - Active: Brightens skin and reduces hyperpigmentation.
  • Tocopherol (Vitamin E): 0.5% - Active: Antioxidant, protects against free radicals, helps stabilise retinaldehyde.

Phase D (Preservative Phase):

  • Phenoxyethanol, Ethylhexylglycerin: 1.0% - Functional: Preservative (broad-spectrum).
  • Potassium Sorbate: 0.3% - Functional: Preservative booster.

Total: 100.00%

Sample Method of Manufacturing:

  1. Phase A: Combine all Phase A ingredients and heat to 70-75°C, mixing until xanthan gum is fully hydrated.
  2. Phase B: Combine all Phase B ingredients and heat to 70-75°C, mixing until uniform.
  3. Emulsification: Slowly add Phase B to Phase A, mixing vigorously using a homogeniser or high-shear mixer until a stable emulsion is formed.
  4. Cooling: Allow the emulsion to cool to below 40°C, stirring occasionally.
  5. Phase C: Add Phase C ingredients one by one, mixing thoroughly after each addition. (Retinaldehyde and peptides are added at this cooler temperature to protect them from heat degradation - this is another example of how formulation decisions directly impact whether your actives actually work.)
  6. Phase D: Add Phase D ingredients, mixing until uniform.
  7. pH Adjustment: Check and adjust the pH to 5.5-6.0 using citric acid or sodium hydroxide if necessary.
  8. Packaging: Package in an airless pump container to protect the retinaldehyde from oxidation.

Why Every Formulation Adds Up to 100%

You might have noticed that all the percentages in the sample formulation above add up to exactly 100% - and that's not a coincidence. Every skincare formulation is built on this principle.

Think of it like a pie - you have 100% of "space" in your formulation, and every single ingredient takes up a portion of that pie.

When we say a serum contains 3% Niacinamide, that means 3 out of every 100 parts of that product is Niacinamide.

This is also why, when you hear people talk about ingredient "strengths" or "percentages" - like a "10% Vitamin C serum" or a "0.05% Retinaldehyde" - they're telling you how much of that 100% is made up of that specific ingredient. It's also why formulation is such a balancing act. 

If you want to increase one ingredient, you have to decrease another to stay at 100%.

You can't just add more of everything. And because every ingredient interacts with the others - affecting texture, stability, pH, absorption, and efficacy - even small changes to those percentages can have a ripple effect across the entire product.

This balance isn't just about performance - it's about safety and stability too.

You couldn't, for example, create a product that's 80-90% active ingredients - it might sound impressive on paper, but without the right balance of solvents to dissolve those actives, emulsifiers to hold the formulation together, preservatives to keep it safe, and stabilisers to stop it from degrading, you'd end up with a product that separates on the shelf, irritates the skin, or becomes a breeding ground for bacteria. 

The functional ingredients aren't taking up space that could go to more actives - they're the reason the actives can do their job safely and effectively in the first place.

This is why two products can list the same "hero" ingredient on the front of the bottle, but perform completely differently.

The individual inclusion percentage matters, but so does what fills the rest of that 100%.